Recombinant tissue plasminogen activator in the treatment of suprachoroidal hemorrhage

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Recombinant tissue plasminogen activator in the treatment of suprachoroidal hemorrhage

BACKGROUND Suprachoroidal hemorrhages are a vision-threatening complication, and poor visual outcome is correlated with increasing hemorrhage complexity. The recommended time of surgical drainage is 10-14 days after the hemorrhage begins to liquefy. We describe a case in which recombinant tissue plasminogen activator (r-tPA), alteplase, is injected within the suprachoroidal space before surgery...

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The Outcome of Treatment With Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke

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Optimizing refolding condition for recombinant tissue plasminogen activator

Low molecular size additives such as L-arginine and the redox compounds have been used both in the culturemedium and in vitro refolding to increase recombinant proteins production. Additives increase proteinrefolding and yield of active proteins by suppressing aggregate formation or enhancing refolding process.In this work, a comparative study was performed on refolding of rec...

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Tissue plasminogen activator-assisted vitrectomy in the early treatment of acute massive suprachoroidal hemorrhage complicating cataract surgery.

Dear Editor, I am Dr. Zhao PQ, from the Department of Ophthalmology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. I write to present a case report of tissue plasminogen activator (tPA)-assisted vitrectomy in the early treatment of acute massive suprachoroidal hemorrhage (SCH) complicating cataract surgery. SCH is a vision-threatening complica...

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Tissue Plasminogen Activator-Assisted Vitrectomy for Ruptured Eye with Suprachoroidal Hemorrhage

PURPOSE To report a case of a ruptured eye with a suprachoroidal hemorrhage (SCH) in which tissue plasminogen activator (tPA)-assisted vitrectomy was successful in reconstructing the globe and restoring good vision. CASE A 32-year-old man was struck on the right eye by a surfboard. His eye was ruptured and his visual acuity decreased to hand movements. Surgery was immediately performed to suc...

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ژورنال

عنوان ژورنال: Clinical Ophthalmology

سال: 2011

ISSN: 1177-5483

DOI: 10.2147/opth.s16134